The Chen Lab investigates metal homeostasis in healthy and diseased neurons using single-molecule techniques, with the goals to understand how metals affect neuronal signaling and cause neurodegenerative diseases. Chen group members will gain valuable experience in state-of-the-art single-molecule microscopy/spectroscopy characterization, molecular biology, and data analyses. Contact Tai-Yen (tchen37@central.uh.edu) to learn about a perfect research project for you!
Tai-Yen present Lab Research at the ACS southwest regional meeting!
We welcome Debbi O'Hair joining us as a graduate student. Welcome!
Guangjie passed his defense! All committees are impressed Guangjie's work. Great Job and congrats again!
Monica, Xihong, Pei-San, and Karen’s paper just got accepted by Open Biology. Congrats!
Tai-Yen gave his first full talk at the Cell Biology of Metal Gordon Research Conference to present our recent finding of CTR1 oligomer study!
The McElrath Postdoctoral Fellowship recognizes postdoctoral associates with a strong documented record of accomplishments (e.g., publications in high-quality peer-reviewed journals and contributed talks at meetings)!
Pei-San, Monica, and Xihong's work has been accepted to Stem Cell Research. They generated of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1, which allows us to study human neuronal antioxdative defense under physiological conditions. Congratulation!
Tai-Yen is selected for the John Butler Teaching award this year for the tenure-track faculty. The John C. Butler Excellence in Teaching Award recognizes faculty in the College of Natural Sciences and Mathematics, who have demonstrated outstanding accomplishments in teaching and a track record of dedication to the teaching mission of NSM. Read more in the UH news
We welcome Alexis Allamprese joining us as a undergraduate student. Alexis is currently a UH undergraduate with chemistry major.
congratulate Guangjie passing his public talk. One more step closer to the Ph.D. degree!
Yuteng presented her work on Cu-dependent intracellular redox behaviors using single-molecule super-resolution microscopy in the Graduate Recurting Weekend (GRW).
Brand new CHEN RESEARCH LAB just arrived!
We welcome Yi-Hung joining us as a research assistant and Patrick as a undergraduate student. Yi-Hung obtained her BS in Pharmacy from Taipei Medical University in 2014 and M.S. in Pharmacology from National Yang-Ming University in 2019. Patrick is currently a UH undergraduate with biochemistry major.
Huanhuan and Yuteng both successfully passed their ORP exams and officially Ph. D. condidates now. Congratulation!
First virtual X'mas party and lucky raffle!
Huanhuan and Xihong's review has been accepted to Current Opinion in Structureal Biology. Huanhuan and Xihong summarized the single-molecule approaches to quantify protein oligomeric stoichiometry in cell in the past 5 years. Congratulation!.
Enjoy the Moon cake at R64!
Manhua, Yuteng, and Guangjie's work has been accepted to Analytical Chemistry. They developed a simulation approach to extract kinetic interaction parameters from single-molecule fluorescence resonance energy transfer trajectories without the need for solving complex differential equations. Congratulation!
UH is preparing for the COVID-19 and will need the list of research staff and graduate student. Please update your information asap in the attached file.Chen Research Group, I bought 10 box of facemasks and just put them in the wetlab. Hope this PPE help everyone protect yourself in this difficult time.
UH is preparing for the COVID-19 and will need the list of research staff and graduate student. Please update your information asap in the attached file.
Huanhuan and Yuteng passed their PChem seminar! First step toward Ph.D. candidate. Congratulation!